지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 333 - 341 (9page)
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초록· 키워드
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Background:Extended-spectrum β-lactamase (ESBL) producing bacteria have been increasingly recognized in the community. The aim of this study was to identify risk factors for community-onset urinary tract infections (UTIs) by ESBL producers in children.
Materials and Methods:We analyzed 854 episodes of community-onset UTIs in children diagnosed at CHA Bundang Medical Center from January, 2004 to April, 2009. The presence of ESBL in Escherichia coli and Klebsiella spp. was screened and confirmed by VITEK®-2 ESBL test. Controls were matched in a 2:1 ratio to case patients by age and sex. The clinical characteristics, risk factors, antimicrobial resistance, and treatment efficacy were compared with controls.
Results:The most common pathogen was Escherichia coli (681 isolates), followed by Klebsiella pneumoniae (60 isolates), Enterococcus faecalis (23 isolates), etc. The number of isolated ESBL producers among the pathogens E. coli and K. pneumoniae was 25 (3.7%) and 7 isolates (11.7%), respectively. No significant differences were noted as to the UTI history prior to the present treatment, underlying urogenital anomaly, and clinical characteristics. Use of any antibiotics within a month (P=0.012, Odds ratio, 6.341, 95% confidence interval, 1.492 to 26.955) was related to the increased risk of community-onset UTI by ESBL producers.
Conclusions:ESBL-producing bacteria has been identified in pediatric community-onset UTI, and the use of any antibiotics within the previous month was related to the increased risk of UTI by ESBL producers. Therefore, careful selection and use of antibiotics should be recommended for community-onset UTI in children.
목차
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참고문헌 (21)
참고문헌 신청
Calbo E / 2006 / Risk factors for community -onset urinary tract infections due to Escherichia coli harbouring extended-spectrum beta-lactamases / J Antimicrob Chemother 57
Cantn R / 2008 / Prevalence and spread of extended-spectrumbeta-lactamase-producing Enterobacteriaceae in Europe / Clin Microbiol Infect 14 Suppl 1 : 144 ~ 153
Colodner R / 2004 / Risk factors for the development of extended-spectrum beta-lactamase-producing bacteria in nonhospitalized patients / Eur J Clin Microbiol Infect Dis 23
Demir S / 2008 / Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in paediatric wards: a nested case-control study / J Paediatr Child Health 44 : 548 ~ 553
Elder JS / 2007 / Urinary tract infections in Nelson textbook of Pediatrics / W.B. Saunders Co.
Cantn R / 2008 / Prevalence and spread of extended-spectrumbeta-lactamase-producing Enterobacteriaceae in Europe / Clin Microbiol Infect 14 Suppl 1 : 144 ~ 153
Colodner R / 2004 / Risk factors for the development of extended-spectrum beta-lactamase-producing bacteria in nonhospitalized patients / Eur J Clin Microbiol Infect Dis 23
Demir S / 2008 / Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in paediatric wards: a nested case-control study / J Paediatr Child Health 44 : 548 ~ 553
Elder JS / 2007 / Urinary tract infections in Nelson textbook of Pediatrics / W.B. Saunders Co.
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