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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 475 - 483 (9page)
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초록· 키워드
오류제보하기
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) has revolutionized the identification of microbial species in clinical microbiology laboratories. MALDI-TOF-MS has swiftly become the new gold-standard method owing to its key advantages of simplicity and robustness. However, as with all new methods, adoption of the MALDI-TOF MS approach is still not widespread. Optimal sample preparation has not yet been achieved for several applications, and there are continuing discussions on the need for improved database quality and the inclusion of additional microbial species. New applications such as in the field of antimicrobial susceptibility testing have been proposed but not yet translated to the level of ease and reproducibility that one should expect in routine diagnostic systems. Finally, during routine identification testing, unexpected results are regularly obtained, and the best methods for transmitting these results into clinical care are still evolving. We here discuss the success of MALDI-TOF MS in clinical microbiology and highlight fields of application that are still amenable to improvement.
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참고문헌 (19)
참고문헌 신청
?edo O / 2011 / Sample preparation methods for MALDI-MS profiling of bacteria / Mass Spectrom Rev 30 : 417 ~ 434
Altun O / 2015 / Rapid identification of bacteria from positive blood culture bottles by MALDI-TOF MS following short-term incubation on solid media / J Med Microbiol 64 : 1
Angeletti S / 2015 / Turnaround time of positive blood cultures after the introduction of matrix-assisted laser desorption-ionization time-of-flight mass spectrometry / New
Curtoni A / 2017 / Rapid identification of microorganisms from positive blood culture by MALDI-TOF MS after short-term incubation on solid medium / Curr Microbiol 74 : 97 ~
Dunne WM Jr / 2014 / Rapid inactivation of Mycobacterium and Nocardia species before identification using matrix-assisted laser desorption ionization-time of flight mass spec
Altun O / 2015 / Rapid identification of bacteria from positive blood culture bottles by MALDI-TOF MS following short-term incubation on solid media / J Med Microbiol 64 : 1
Angeletti S / 2015 / Turnaround time of positive blood cultures after the introduction of matrix-assisted laser desorption-ionization time-of-flight mass spectrometry / New
Curtoni A / 2017 / Rapid identification of microorganisms from positive blood culture by MALDI-TOF MS after short-term incubation on solid medium / Curr Microbiol 74 : 97 ~
Dunne WM Jr / 2014 / Rapid inactivation of Mycobacterium and Nocardia species before identification using matrix-assisted laser desorption ionization-time of flight mass spec
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Applications of MALDI-TOF Mass Spectrometry in Clinical Microbiology
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MALDI-TOF MS의 임상검사실 내 적용과 미생물검사의 패러다임 변화
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Utility of Conventional Culture and MALDI-TOF MS for Identification of Microbial Communities in Bronchoalveolar Lavage Fluid in Comparison with the GS Junior Next Generation Sequencing System
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MALDI-TOF 질량분석기를 이용한 바실러스균의 동정
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Performance of Matrix-Assisted Laser Desorption Ionization Time-of-Fight Mass Spectrometry for Rapid Discrimination of Methicillin-Resistant Staphylococcus aureus (MRSA): First Report of a Relation Between Protein Peaks and MRSA spa Type
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Performance of Microflex LT Biotyper and VITEK MS for Routine Identification of Yeasts
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Performance Comparison Between Fourier-Transform Infrared Spectroscopy–based IR Biotyper and Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry for Strain Diversity
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Evaluation of Two Commercial Kits for Rapid Pathogen Identification Directly From Positive Blood Cultures by Matrix-Associated Laser Desorption/Ionization Time-of-Flight Mass Spectrometry
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Direct Identification and Antimicrobial Susceptibility Testing of Bacteria From Positive Blood Culture Bottles by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry and the Vitek 2 System
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Novel analysis procedure for red ginseng polysaccharides by matrix-assisted laser desorption/ionization time-of-flight/time-of-flight mass spectrometry
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Identification of Acinetobacter Species Using Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry
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Application of the Whole Genome-Based Bacterial Identification System, TrueBac ID, Using Clinical Isolates That Were Not Identified With Three Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) Systems
Annals of Laboratory Medicine
2019 .01
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Comparison of MALDI-TOF MS, Housekeeping Gene Sequencing, and 16S rRNA Gene Sequencing for Identification of Aeromonas Clinical Isolates
Yonsei Medical Journal
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Direct Identification of Urinary Tract Pathogens From Urine Samples Using the Vitek MS System Based on Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry
Annals of Laboratory Medicine
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Simple measurement the chelator number of antibody conjugates by MALDI-TOF MS
대한방사성의약품학회지
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Resource Development and Investigation of Novel Species from Unidentified Pathogens in NCCP using MALDI-TOF MS and 16S rRNA Gene Analysis
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2016 .12
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Availability of MADLDI-TOF MS for Identification of Gram Positive Bacilli Isolated from Blood Culture
대한의생명과학회지
2018 .06
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Substantial Improvement in Nontuberculous Mycobacterial Identification Using ASTA MicroIDSys Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry with an Upgraded Database
Annals of Laboratory Medicine
2022 .05
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Evaluation of VITEK Mass Spectrometry (MS), a Matrix-Assisted Laser Desorption Ionization Time-of-Flight MS System for Identification of Anaerobic Bacteria
Annals of Laboratory Medicine
2015 .01
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