두경부암에서 기존의 영상기법과의 비교를 통한 PET-CT의 임상적 유용성

김재원; 김영모; 윤석영; 이승호; 고국진

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자료유형: 학술저널

저자정보: 김재원 김영모 윤석영 이승호 고국진

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제49권 제10호

발행연도: 2006.1

수록면: 1,014 - 1,017 (4page)

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연구결과

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Background and Objectives：In head & neck cancer, the conventional CT and MRI are useful methods in imaging the anatomicalstructures of cancer, but they have limits in estimating sensitivity and specificity. To overcome these limits, PET-CT, animaging technique using metabolism emitting from cancer tissues, was introduced. This study was aimed to evaluate the clinicalvalues of PET-CT by comparing the PET-CT of the conventional CT/MRI, with respect to imaging primary lesions, finding metastaticcervical lymph nodes, and discovering any tumor or recurrence. Materials and Method：Seventy patients, who werediagnosed with head and neck cancer, were selected from Inha Hospital from March, 2004 to July, 2005. For every patient selected,a retrospective analysis was done by medical record review. The studied patients were divided into group 1 and 2. Group1 was composed of patients that had preoperative evaluation for staging, group 2 with follow-up patients after primary treatment.In group 1, the analysis was done by comparing pathohistologic results from PET-CT to CT/MRI findings and in group 2, radiologicimaging studies were compared by follow-up imaging or clinical manifestation after 6 months. Results：For the primarysites, 22 cases were laryngeal cancers, and 17 cases were thyroid. For primary site cancers and metastatic lymph nodes in group1 and 2, there were no statistical differences of sensitivity, specificity and predictability between CT/MRI and PET-CT imaging.Conclusion：We were not able to prove the clinical values of PET-CT, since PET-CT had no meaningful differences from the conventionalmethods in imaging primary lesions, finding metastatic cervical lymph nodes, and follow-up. (Korean J Otolaryngol2006;49:1014-7)

#양전자방출단층촬영술·두경부암. #Positron emission tomography·Head and neck cancer.

참고문헌 (10)

참고문헌 신청

Abdel-Nabi H / 1998 / Staging of primary colorectal carcinoma withfluorine-18 fluorodeoxyglucose whole-body PET:Correlation withhistopathologic and CT findings 206 : 755 ~ 76

Antoch G / 2004 / Accuracy of whole-body dual-modality fluorine-18-2-fluoro-2-de-ixyd-glucose positron emission tomography and computed tomography(FDG-PET/CT) for tumor stagi

Gutzeit A / 2005 / Unknown primary tumor:Detection with dual-modality PET/CTinitialexperience 234 : 227 ~ 234

Kapoor V / 2005 / Role of 18FFDG PET/CT in thetreatment of head and neck cancer:Posttherapy evaluation and pitfalls 184 : 589 ~ 597

Muylle K / 2005 / 18F-fluoro-2-deoxy-D-glucose positronemission tomographic imaging:Recent developments in headand neck cancer 17 : 249 ~ 253

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