Association between body composition measured by bioelectrical impedance analysis and platelet-to-lymphocyte ratio in colorectal cancer

Woo Jin Song; Kyeong Eui Kim; Sung Uk Bae; Woon Kyung Jeong; Seong Kyu Baek

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자료유형: 학술저널

저자정보: Woo Jin Song (Keimyung University School of Medicine) Kyeong Eui Kim (Keimyung University School of Medicine) Sung Uk Bae (Keimyung University School of Medicine) Woon Kyung Jeong (Keimyung University School of Medicine) Seong Kyu Baek (Keimyung University School of Medicine)

저널정보: 대한종양외과학회 KOREAN JOURNAL OF CLINICAL ONCOLOGY Korean Journal of Clinical Oncology 제15권 제1호

발행연도: 2019.6

수록면: 7 - 14 (8page)

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Purpose: This study investigated the relationship between body composition and platelet-to-lymphocyte ratio (PLR) in patients with colorectal cancer (CRC).
Methods: This retrospective study included 110 patients who underwent anthropometric measurement by bioelectrical impedance analysis before surgical treatment for CRC between May 2015 and June 2018.
Results: According to PLR, 45 patients (40.9%) had low PLR (PLR<150), and 65 patients (59.1%) had high PLR (PLR≥150). Serum hemoglobin (P<0.001) and albumin levels (P=0.021) were significantly lower in high PLR group. Tumor mass diameter was significantly larger in high PLR group (P=0.048) and the proportion of poorly differentiated or mucinous tumors was significantly higher in high PLR group (P=0.037). All indices related to fat (body fat mass, percent body fat, body fat mass of trunk, visceral fat area, fat mass index, measured fat thickness of abdomen) and two indices related to muscle (arm muscle circumference, measured muscle circumference of abdomen) were significantly lower in high PLR group (P<0.05). According to subgroup analysis based on the sex, all indices significantly differed between PLR groups; however, in females no index was significantly different between PLR groups.
Conclusion: Body composition indices including fat and muscle indices measured by InBody 770 were related to PLR in CRC, especially in male patients. These results suggest that low muscle and fat indices may be related to poor prognosis of CRC.

#Colorectal neoplasm #Nutrition assessment #Body composition #Electric impedance #Prognosis

참고문헌 (24)

참고문헌 신청

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Balkwill F / 2001 / Inflammation and cancer: back to Virchow? / Lancet 357:539~545

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