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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 843 - 851 (9page)
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This study investigated the association between OCS and the long-term prognosis of ACS in tandem with depression comorbidity and treatment. Methods A cross-sectional baseline study and a nested 24-week double-blind escitalopram-placebo controlled trial were carried out between May 2007 and March 2013, and then a 5–12-year follow-up for major adverse cardiac events (MACE) was conducted. A total of 1,152 patients with ACS were stratified by baseline depression comorbidity and treatment allocation into four groups: no depression (706 patients), depression and taking escitalopram (149 patients), depression and taking a placebo (151 patients), and depression and receiving medical care as usual (CAU; 146 patients). OCS were evaluated using the Symptom Checklist-90-Revised Obsessive-Compulsive symptom domain. During the follow-up, Kaplan-Meier event rates for MACE outcomes were calculated, and hazard ratios were estimated using Cox regression models after adjusting for a range of covariates. Results A higher OCS score at baseline was associated with a worse ACS prognosis after adjusting for relevant covariates and across MACE outcomes. This association varied according to the depression comorbidity. The association was significant in patients without depression and depressive patients receiving placebos and CAU, but not in depressive patients on escitalopram. Conclusion Evaluating OCS and depression is recommended during the early phase of ACS. Treatment for OCS may improve the longterm cardiac outcomes of patients with ACS.
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참고문헌 (40)
참고문헌 신청
Johansson S / 2017 / Mortality and morbidity trends after the first year in survivors of acute myocardial infarction : a systematic review / BMC Cardiovasc Disord 17:53
Kuper H / 2002 / Systematic review of prospective cohort studies of psychosocial factors in the etiology and prognosis of coronary heart disease / Semin Vasc Med 2:267~314
American Psychiatric Association / 2013 / Diagnostic and Statistical Manual of Mental Disorders / American Psychiatric Association
Bezgin CH / 2016 / Temperament and character profiles and psychiatric comorbidities in patients with coronary artery or valvular heart disease : relationship with cardiac disease severity / J Clin Med Res 8:202~209
Hamideh pour OJ / 2014 / Compare the obsessive-compulsive disorders between coronary heart disease and healthy subjects / J Nov Appi Sci 3:283~286
Kuper H / 2002 / Systematic review of prospective cohort studies of psychosocial factors in the etiology and prognosis of coronary heart disease / Semin Vasc Med 2:267~314
American Psychiatric Association / 2013 / Diagnostic and Statistical Manual of Mental Disorders / American Psychiatric Association
Bezgin CH / 2016 / Temperament and character profiles and psychiatric comorbidities in patients with coronary artery or valvular heart disease : relationship with cardiac disease severity / J Clin Med Res 8:202~209
Hamideh pour OJ / 2014 / Compare the obsessive-compulsive disorders between coronary heart disease and healthy subjects / J Nov Appi Sci 3:283~286
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