지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
We compared impulsive behaviors in Wistar rats and in Wistar-Kyoto rats. There was no significant difference in locomotor activity between them. However, Wistar rats showed high activity in 5-choice serial reaction time track. When Wistar rats were treated with atomoxetin (3 mg/kg), methylphenidate (2 mg/kg) or amphetamine (2 mg/kg), they showed less impulsive behavior. Serotonin contents in prefrontal cortex and brain stem also increased. In conclusion, we suggest that Wistar rats could be used as animal model for impulsive behavior analysis. In addition, serotonin might be related with this impulsivity.
목차
등록된 정보가 없습니다.
참고문헌 (34)
참고문헌 신청
Clause, B. T / 1998 / The Wistar Institute Archives: Rats (Not Mice)and History / Mendel Newsl (7):2
Bizot, J. C / 2007 / Methylphenidate reduces impulsive behaviour in juvenile Wistar rats, but not in adult Wistar, SHR and WKY rats / Psychopharmacology (Berl) 193:215
Drolet, G / 2002 / Comparisons of behavioral and neurochemical characteristics between WKY, WKHA, and Wistar rat strains / Neuropsychopharmacolog 27:400
Ibias, J / 2014 / Different relations between scheduleinduced polydipsia and impulsive behaviour in the Spontaneously Hypertensive Rat and in high impulsive Wistar rats: Questioning the role of impulsivity in adjunctive behaviour / Behav. Brain. Res 271:184
Zhang-James, Y / 2013 / Genetic architecture of Wistar-Kyoto rat and spontaneously hypertensive rat substrains from different sources / Physiol. Genomics 45:528
Bizot, J. C / 2007 / Methylphenidate reduces impulsive behaviour in juvenile Wistar rats, but not in adult Wistar, SHR and WKY rats / Psychopharmacology (Berl) 193:215
Drolet, G / 2002 / Comparisons of behavioral and neurochemical characteristics between WKY, WKHA, and Wistar rat strains / Neuropsychopharmacolog 27:400
Ibias, J / 2014 / Different relations between scheduleinduced polydipsia and impulsive behaviour in the Spontaneously Hypertensive Rat and in high impulsive Wistar rats: Questioning the role of impulsivity in adjunctive behaviour / Behav. Brain. Res 271:184
Zhang-James, Y / 2013 / Genetic architecture of Wistar-Kyoto rat and spontaneously hypertensive rat substrains from different sources / Physiol. Genomics 45:528
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