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Bioaccessibility of β-Lactoglobulin Nanoemulsions Containing Coenzyme Q<sub>10</sub>: Impact of Droplet Size on the Bioaccessibility of Coenzyme Q<sub>10</sub>
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논문 기본 정보

Type
Academic journal
Author
Ha, Ho-Kyung (Department of Animal Science and Technology, Sunchon National University) Lee, Mee-Ryung (Department of Food and Nutrition, Daegu University) Lee, Won-Jae (Department of Animal Bioscience [Institute of Agriculture and Life Science], Gyeongsang National University)
Journal
한국축산식품학회 한국축산식품학회지 한국축산식품학회지 제38권 제6호 KCI Accredited Journals
Published
2018.1
Pages
1,294 - 1,304 (11page)

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Bioaccessibility of β-Lactoglobulin Nanoemulsions Containing Coenzyme Q<sub>10</sub>: Impact of Droplet Size on the Bioaccessibility of Coenzyme Q<sub>10</sub>
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The aims of this research were to examine the effect of heating temperature (65, 75, and $85^{\circ}C$) and $CaCl_2$ concentration level (3, 4, and 5 mM) on the physicochemical properties of ${\beta}$-lactoglobulin (${\beta}$-lg) nanoemulsions (NEs) and to study how the droplet size of NEs affects the bioaccessibility (BA) of coenzyme $Q_{10}$ ($CoQ_{10}$). The droplet size of NEs and BA of $CoQ_{10}$ was assessed by particle size analyzer and UV-Vis spectrophotometer, respectively. An increase in heating temperature and $CaCl_2$ concentration level resulted in a significant (p<0.05) increase in the droplet size of NEs while there were no significant differences in polydispersity index and zeta-potential of NEs. When NEs containing $CoQ_{10}$ were incubated in simulated small intestinal phases, an increase in the droplet size and polydispersity index of NEs was observed. This indicated that NEs were not stable in small intestine and digestion of NEs occurred. As heating temperature and $CaCl_2$ concentration level were decreased, a significant (p<0.05) increase in BA of $CoQ_{10}$ was observed. There was a significant (p<0.05) increase in BA of $CoQ_{10}$ with a decrease in the droplet size of NEs. In conclusion, heating temperature and $CaCl_2$ concentration level were key-parameters affecting the initial droplet size of NEs and BA of $CoQ_{10}$ was negatively correlated with initial droplet size of NEs.
#${beta}$-lactoglobulin #nanoemulsion #coenzyme $Q_{10}$ #droplet size #bioaccessibility

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