지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
Sirtuin proteins are evolutionary conserved Sir2-related $NAD^+$-dependent deacetylases and regulate many of cellular processes such as metabolism, inflammation, transcription, and aging. Sirtuin contains activity of either ADP-ribosyltransferase or deacetyltranfease and their activity is dependent on the localization in cells. However, the expression pattern of Sirtuins has not been well studied. To examine the expression levels of Sirtuins, RT-PCR was performed using total RNAs from various tissues including liver, small intestine, heart, brain, kidney, lung, spleen, stomach, uterus, ovary, and testis. Sirtuins were highly expressed in most of tissues including the testis. Immunostaining assay showed that Sirt1 and Sirt6 were mainly located in the nucleus of germ cells, spermatocytes, and spermatids in the seminiferous tubules, whereas Sirt2 and Sirt5 were exclusively present in the cytoplasm of germ cells and spermatocytes. Our results indicate that Sirtuins may function as regulators of spermatogenesis and their activities might be dependent on their location in the seminiferous tubules.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
유아용 당류섭취저감도검사 도구 개발
한국식품영양학회지
2016 .10
-
Whey Protein Attenuates Angiotensin II-Primed Premature Senescence of Vascular Smooth Muscle Cells through Upregulation of SIRT1
한국축산식품학회지
2017 .01
-
Duck Oil-loaded Nanoemulsion Inhibits Senescence of Angiotensin II-treated Vascular Smooth Muscle Cells by Upregulating SIRT1
Food science of animal resources
2020 .01
-
Sirt1-Mediated Anti-Aging Effects of Houttuynia cordata Extract in a High Glucose-Induced Endothelial Cell-Aging Model
Preventive Nutrition and Food Science
2020 .03
-
Activation of SIRT1 Promotes Epidermal Permeability Barrier Function through Ceramide Synthase 2- and 3-Dependent Mechanisms
한국식품영양과학회 학술대회발표집
2020 .10
-
Implications of SIRT3-IDH2 axis on radiotherpay-induced liver toxicity
한국식품영양과학회 학술대회발표집
2024 .10
-
Ellagic Acid Induce Beige Remodeling of White Adipose Tissue by Controlling SIRT3-Mediated Mitochondrial Dynamics
한국식품영양과학회 학술대회발표집
2022 .10
-
Sirt1-Mediated Anti-Senescent Effects of Houttuynia cordata Extract in a High Glucose-Induced Senescence in Endothelial Cells
한국식품영양과학회 학술대회발표집
2020 .10
-
SIRT1 Contributes to Enhance Epidermal Permeability Barrier Function Through Activation of Ceramide-Metabolizing Enzymes
한국식품영양과학회 학술대회발표집
2021 .10
-
Protective effects of Aralia elata (Miq.) Seem. on high glucose-accelerated senescence in human umbilical vein endothelial cells through SIRT1 activation
한국식품영양과학회 학술대회발표집
2019 .10
-
Tartary Buckheat Extract Regulates Adipose Tissue Inflammatory M1/M2 Macrophages and Muscle PGC-1a/SIRT1 Pathway in Rats Fed a High-fat Diet
한국식품영양과학회 학술대회발표집
2018 .10
-
D-Allulose ameliorates hyperglycemia and obesity through IRE1α sulfonation-RIDD axis; the involvement of SIRT1 & GLP1R
한국식품영양과학회 학술대회발표집
2023 .10
-
황정 에탄올 추출물의 비만 조절 유전자에 대한 효과
한국식품과학회지
2016 .08
-
Ginger Extract Ameliorates Lipid Accumaulation and Endoplasmic Reticulum Stress of Adipose Tissues by SIRT-1-PGC-1α Signaling via AMPK Activation in ob/ob mice
한국식품영양과학회 학술대회발표집
2022 .10
-
Effect of Turmeric Supplementation on Blood Pressure and Serum Levels of Sirtuin 1 and Adiponectin in Patients with Nonalcoholic Fatty Liver Disease: A Double-Blind, Randomized, Placebo-Controlled Trial
Preventive Nutrition and Food Science
2022 .03
-
Hydroethanolic extract of Cirsium setidens (CSE) protects against doxorubicin-induced cardiotoxicity via modulating AMPK/SIRT1/PGC-1α signaling pathway mediated mitochondrial function, apoptosis
한국식품영양과학회 학술대회발표집
2022 .10
-
고지방식이로 비만이 유도된 마우스에서 황정 주정 추출물의 항비만 효과
한국식품과학회지
2015 .08
-
Raphanus sativus L. var. caudatus Extract Alleviates Impairment of Lipid and Glucose Homeostasis in Liver of High-Fat Diet-Induced Obesity and Insulin Resistance in Mice
Preventive Nutrition and Food Science
2022 .12
-
Optimization of Extraction Conditions for Ethanol Extracts of Humulusjaponicas and Antioxidant Activity
한국약용작물학회 학술대회논문집
2021 .05
-
Extracts of abalone intestine regulates fat metabolism in 3T3-L1 adipocytes and high fat dietinduced zebrafish larvae
Fisheries and Aquatic Sciences
2024 .02
이 논문의 저자 정보
최근 본 자료
댓글(0)
0