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논문 기본 정보

자료유형
학술저널
저자정보
Hwang Jin Ho (Division of Nephrology Department of Internal Medicine Chung-Ang University Hospital Seoul Korea.) Hwang Hyunchan (Department of Psychiatry Chung-Ang University Hospital Seoul Korea.) Kim Hye Ri (Department of Psychiatry Chung-Ang University Hospital Seoul Korea.) Hong Ji Sun (Department of Psychiatry Chung-Ang University Hospital Seoul Korea.) Han Doug Hyun (Department of Psychiatry Chung-Ang University Hospital Seoul Korea.) Shin Jung-ho (Division of Nephrology Department of Internal Medicine Chung-Ang University Hospital Seoul Korea.) Kim Su Hyun (Division of Nephrology Department of Internal Medicine Chung-Ang University Hospital Seoul Korea.) 김선미 (중앙대학교)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.35 No.26
발행연도
2020.1
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1 - 13 (13page)

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Background: This study aimed to evaluate the therapeutic effect of repetitive transcranial magnetic stimulation (rTMS) as a nonpharmacologic treatment in depressed hemodialysis patients. Methods: Patients who scored ≥ 5 on the Patient Health Questionnaire-9 were randomized to either the rTMS (n = 7) or sham group (n = 7). The rTMS group was stimulated with a 110% motor threshold and 10 Hz on the left dorsolateral prefrontal cortex for 20 minutes, three times a week, for 4 weeks. In the sham group, the “1-wing 90-degree method” was used. We analyzed clinical indices before and after the intervention, as well as data from quantitative electroencephalography (frontal alpha asymmetry [FAA]), and various psychiatric questionnaires (Beck Depression Inventory-II, Beck Anxiety Inventory [BAI], Symptom Checklist-90-Revised Somatization Subscale [SCL-90R-SOM]), and Perceived Stress Scale. Results: One month after rTMS, the changes in hemoglobin A1c levels in the rTMS group were significantly greater than those in the sham group (F = 6.687, P = 0.032). The changes in BAI scores in the rTMS group were significantly greater than those in the sham group (F = 6.700, P = 0.025), and the changes in SCL-90R-SOM scores in the rTMS group were greater than those in the sham group (F = 4.943, P = 0.048). In addition, the changes in the FAA value at the F7 and F8 electrodes in the rTMS group were greater than those in the sham group (F = 6.468, P = 0.027). Conclusion: In depressed hemodialysis patients, rTMS may improve anxiety and somatization symptoms, which may lead to improvements in clinical measures.

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