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논문 기본 정보

자료유형
학술저널
저자정보
Seung Young Kim (Division of Gastoenterology and Hepatology Department of Internal Medicine Korea University Ansan H) Rok Seon Choung (Division of Gastroenterology and Hepatology Mayo Clinic Rochester Minnesota USA) Seung Ku Lee (Institute of Human Genomic Study Korea University Ansan Hospital Ansan Korea) 최정완 (고려대학교) Sung Woo Jung (Division of Gastoenterology and Hepatology Department of Internal Medicine Korea University Ansan H) Jong Jin Hyun (Division of Gastoenterology and Hepatology Department of Internal Medicine Korea University Ansan H) Ja Seol Koo (Division of Gastoenterology and Hepatology Department of Internal Medicine Korea University Ansan H) Sang Woo Lee (Division of Gastoenterology and Hepatology Department of Internal Medicine Korea University Ansan H) Chol Shin (Institute of Human Genomic Study Korea University Ansan Hospital Ansan Korea)
저널정보
대한소화관운동학회(현 대한소화기능성질환.운동학회) Journal of Neurogastroenterology and Motility (JNM) Journal of Neurogastroenterology and Motility (JNM) Vol.24 No.2
발행연도
2018.1
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280 - 288 (9page)

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Background/Aims Sleep impairment is a common complaint among patients with irritable bowel syndrome (IBS) and functional dyspepsia (FD). This study aimed to evaluate the prevalence of sleep impairment in FD or IBS patients, and to determine whether IBS-FD overlap induced more sleep disturbance than FD or IBS alone. Methods A population-based cohort in South Korea including 2251 subjects was asked about gastrointestinal symptoms including IBS and dyspepsia-related symptoms. In addition, sleep disturbance was measured using the Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale questionnaires. One-way ANOVA and logistic regression were used to assess differences among the 4 groups (healthy subjects, IBS alone, FD alone, and IBS-FD overlap). Results Of 2251 subjects who were surveyed by questionnaire, 2031 responded (92.5% response rate) and were analyzed. The prevalence of IBS, FD, and IBS-FD overlap was 8.0% (95% confidence interval [CI], 6.8–9.2%), 4.8% (95% CI, 3.9–5.8%), and 1.8% (95% CI, 1.2–2.4%), respectively. FD alone, but not IBS alone, was significantly associated with a poorer sleep quality index (OR, 2.68; 95% CI, 1.43–5.01) and more daytime sleepiness (OR, 2.21; 95% CI, 1.14–4.30), compared to healthy subjects. IBS-FD overlap had the greatest likelihood of a poorer sleep quality index (OR, 3.88; 95% CI, 1.83–8.19), daytime sleepiness (OR, 2.47; 95% CI, 1.01–5.67), and insomnia (OR, 2.84; 95% CI, 1.39–5.82), compared to healthy subjects. Conclusion A correlation between functional gastrointestinal disorders and sleep disturbance was demonstrated, which was significantly pronounced in the context of IBS-FD overlap.

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참고문헌 (42)

참고문헌 신청
Weissman MM / 1997 / The morbidity of insomnia uncomplicated by psychiatric disorders / Gen Hosp Psychiatry 19:245~250 Crossref Parish JM / 2009 / Sleep-related problems in common medical conditions / Chest 135:563~572 Crossref Smagula SF / 2016 / Chronic disease and lifestyle factors associated with change in sleep duration among older adults in the Singapore Chinese health study / J Sleep Res 25:57~61 Crossref Dickman R / 2007 / Relationships between sleep quality and pH monitoring findings in persons with gastroesophageal reflux disease / J Clin Sleep Med 3:505~513 google schola Hiroshi Yamawaki / 2014 / Impact of Sleep Disorders, Quality of Life and Gastric Emptying in Distinct Subtypes of Functional Dyspepsia in Japan / Journal of Neurogastroenterology and Motility (JNM) 20(1):104~112 dbpia

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