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논문 기본 정보

자료유형
학술저널
저자정보
Kim Yu Kyung (Department of Clinical Pathology School of Medicine Kyungpook National University Daegu Korea.) Minn Dohsik (Department of Diagnostic Immunology Seegene Medical Foundation Seoul Korea.) Song Do Young (Department of Laboratory Medicine Daegu Fatima Hospital Daegu Korea.) Lee Chae Hoon (Department of Laboratory Medicine Yeungnam University College of Medicine Daegu Korea.) Ryoo Nam Hee (Department of Laboratory Medicine Keimyung University School of Medicine Daegu Korea.) Jeon Chang-Ho (Department of Laboratory Medicine Daegu Catholic University Hospital Daegu Korea.) Song Kyung Eun (Department of Clinical Pathology School of Medicine Kyungpook National University Daegu Korea.Depar) Suh Jang Soo (Department of Clinical Pathology School of Medicine Kyungpook National University Daegu Korea.) Chang Soon Hee (Department of Clinical Pathology School of Medicine Kyungpook National University Daegu Korea.)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.36 No.43
발행연도
2021.11
수록면
1 - 9 (9page)
DOI
10.3346/jkms.2021.36.e294

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Background: In Korea, the first community outbreak of coronavirus disease 2019 (COVID-19) occurred in Daegu on February 18, 2020. This study was performed to investigate the prevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) antibodies in healthcare workers (HCWs) at 6 major hospitals in Daegu. Methods: Blood specimens of 2,935 HCWs at 6 major hospitals in Daegu from January 2021 to February 2021 were collected. Every specimen was tested for antibody against SARS-CoV-2 using both Elecsys Anti-SARS-CoV-2 electrochemiluminescence immunoassay (Roche Diagnostics, Rotkreuz, Switzerland) and R-FIND COVID-19 IgG/M/A enzyme-linked immunosorbent assay kit (SG medical Inc., Seoul, Korea) as screening tests. If 1 or more of these screening test results was positive, 2 additional antibody tests were performed using Abbott Anti-SARS-CoV-2 IgG assay (Abbott, Abbott Park, IL, USA) and cPass SARS-CoV-2 Neutralization Antibody Detection Kit (GenScript USA Inc., Piscataway, NJ, USA). If 2 or more of the total 4 test results were positive, it was determined as positive for the antibody against SARS-CoV-2. Results: According to the criteria of SARS-CoV-2 antibody positivity determination, 12 subjects were determined as positive. The overall positive rate of the SARS-CoV-2 antibody was 0.41% (12/2,935). Of the 12 subjects determined as positive, 7 were diagnosed with COVID-19, and the remaining 5 were nondiagnosed cases of COVID-19. Conclusion: In early 2021, the overall seroprevalence of SARS-CoV-2 antibody among HCW located in Daegu was 0.41%, and 0.17% excluding COVID-19 confirmed subjects. These results were not particularly high compared with the general public and were much lower than HCWs in other countries.
#COVID-19 #SARS-CoV-2 Antibody #Healthcare Worker #Neutralizing Antibody

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참고문헌 (12)

참고문헌 신청
Ministry of Health and Welfare (KR) / Coronavirus disease-19, Republic of Korea google schola 김신우 / 2020 / A Brief Telephone Severity Scoring System and Therapeutic Living Centers Solved Acute Hospital-Bed Shortage during the COVID-19 Outbreak in Daegu, Korea / Journal of Korean Medical Science 35(15):1~6 dbpia Ko JH / 2020 / Serologic evaluation of healthcare workers caring for COVID-19 patients in the Republic of Korea / Front Microbiol 11:587613 google schola Daegu Metropolitan City Hall / Daegu Metropolitan City COVID-19 status google schola Galanis P / 2021 / Seroprevalence of SARS-CoV-2 antibodies and associated factors in healthcare workers : a systematic review and meta-analysis / J Hosp Infect 108:120~134 google schola

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