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논문 기본 정보

자료유형
학술저널
저자정보
Kim Sun Bean (Division of Infectious Diseases Department of Internal Medicine Korea University College of Medicin) Kim Jimin (Division of Healthcare Technology Assessment Research National Evidence-based Healthcare Collaborat) Huh Kyungmin (Division of Infectious Diseases Department of Internal Medicine Samsung Medical Center Sungkyunkwan) Choi Won Suk (Division of Infectious Diseases Department of Internal Medicine Korea University College of Medicin) Kim Yae-Jean (Division of Infectious Diseases and Immunodeficiency Department of Pediatrics Samsung Medical Cente) Joo Eun-Jeong (Division of Infectious Diseases Department of Internal Medicine Sungkyunkwan University School of M) Kim Youn Jeong (Division of Infectious Diseases Department of Internal Medicine Incheon St. Mary's Hospital College) Yoon Young Kyung (Division of Infectious Diseases Department of Internal Medicine Korea University College of Medicin) Heo Jung Yeon (Department of Infectious Diseases Ajou University School of Medicine Suwon Korea.) Seo Yu Bin (Division of Infectious Diseases Department of Internal Medicine Hallym University College of Medici) Jeong Su Jin (Department of Internal Medicine Severance Hospital Yonsei University College of Medicine Seoul Kore) Yu Su-Yeon (Division of Healthcare Technology Assessment Research National Evidence-based Healthcare Collaborat) Peck Kyong Ran (Division of Infectious Diseases Department of Internal Medicine Samsung Medical Center Sungkyunkwan) Choi Miyoung (Division of Healthcare Technology Assessment Research National Evidence-based Healthcare Collaborat) Yeom Joon Sup (Department of Internal Medicine Severance Hospital Yonsei University College of Medicine Seoul Kore)
저널정보
대한감염학회 Infection and Chemotherapy Infection and Chemotherapy 제53권 제2호
발행연도
2021.1
수록면
395 - 403 (9page)

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초록· 키워드

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Neutralizing antibodies targeted at the receptor-binding domain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein have been developed and now under evaluation in clinical trials. The US Food and Drug Administration currently issued emergency use authorizations for neutralizing monoclonal antibodies in non-hospitalized patients with mild to moderate coronavirus disease 2019 (COVID-19) who are at high risk for progressing to severe disease and/or hospitalization. In terms of this situation, there is an urgent need to investigate the clinical aspects and to develop strategies to deploy them effectively in clinical practice. Here we provide guidance for the use of anti-SARS-CoV-2 monoclonal antibodies for the treatment of COVID-19 based on the latest evidence.
#COVID-19 #Anti-SARS-CoV-2 monoclonal antibody #Korea

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참고문헌 (15)

참고문헌 신청
Wang C / 2020 / A human monoclonal antibody blocking SARS-CoV-2 infection / Nat Commun 11:2251 google schola Yang Y / 2021 / SARS-CoV-2 spike protein: a key target for eliciting persistent neutralizing antibodies / Signal Transduct Target Ther 6:95 google schola Kim Sun Bean / 2021 / Revised Korean Society of Infectious Diseases/National Evidence-based Healthcarea Collaborating Agency Guidelines on the Treatment of Patients with COVID-19 / Infection and Chemotherapy 53(1):166~219 dbpia Gottlieb RL / 2021 / Effect of bamlanivimab as monotherapy or in combination with etesevimab on viral load in patients with mild to moderate COVID-19: a randomized clinical trial / JAMA 325:632~644 google schola Chen P / 2021 / SARS-CoV-2 neutralizing antibody LY-CoV555 in outpatients with Covid-19 / N Engl J Med 384:229~237 google schola

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