지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.12
- 수록면
- 294 - 301 (8page)
- DOI
- 10.1186/s40824-016-0080-4
이용수
초록· 키워드
오류제보하기
Background: Auxetic scaffolds (experimental) was fabricated by using poly(D, L-lactic-co-glycolic acid), 50:50, (PLGA) for effective bone cell proliferation with mechanical stimulation. Methods: Negative Poisson’s ratio in scaffold, 3-directional volumetric compression was applied during the scaffold fabrication at adequate temperature (60 °C). The pore size of scaffold ranged between 355 and 400 μm. Results: The porous morphology of the prepared auxetic scaffolds had shown partially concave and dent shapes in SEM image as expected. The lowest Poisson’s ratios of experimental group was ?0.07 at 60 °C/10 min. Compressive strength of experimental group was shown about 3.12 times higher than control group (conventional scaffold) in dry state at 25 °C. The compressive strengths of both groups were tended to be decreased dramatically in wet state compared to in dry state. However, compressive strengths of experimental group were higher 3.08 times and 1.88 times in EtOH/PBS (25 °C) and EtOH/PBS/DMEM (37 °C) than control group in wet state, respectively. Degradation rate of the scaffolds showed about 16 % weight loss in 5 weeks. In cell attachment test, experimental group showed 1.46 times higher cell proliferation than control group at 1-day with compressive stimulation. In 3-day culture, the experimental group showed 1.32 times higher than control group. However, there was no significant difference in cell proliferation in 5-day cultivation. Conclusion: Overall, negative Poisson’s ratio scaffolds with static mechanical stimulation could affect the cell proliferation at initial cultivation time.
목차
등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
Yoon JJ / 2001 / Degradation behaviors of biodegradable macroporous scaffolds prepared by gas foaming of effervescent salts / J Biomed Mater Res 55:401~408
Jun Jae Lee / 2007 / Investigation on biodegradable PLGA scaffold with various pore size structure for skin tissue engineering / Current Applied Physics 7(s1):37~40
Oh SH / 2007 / In vitro and in vivo characteristic of PCL scaffold with pore size gradient fabricated by a centrifugation method / Biomaterials 28:1664~1671
Hou Q / 2003 / Porous polymeric structures for tissue engineering prepared by a coagulation, compression moulding and salt leaching technique / Biomaterials 24:1937~1947
Wu L / 2006 / “Wet-state” mechanical properties of threedimensional polyester porous scaffolds / J Biomed Mater Res 76A:264~271
Jun Jae Lee / 2007 / Investigation on biodegradable PLGA scaffold with various pore size structure for skin tissue engineering / Current Applied Physics 7(s1):37~40
Oh SH / 2007 / In vitro and in vivo characteristic of PCL scaffold with pore size gradient fabricated by a centrifugation method / Biomaterials 28:1664~1671
Hou Q / 2003 / Porous polymeric structures for tissue engineering prepared by a coagulation, compression moulding and salt leaching technique / Biomaterials 24:1937~1947
Wu L / 2006 / “Wet-state” mechanical properties of threedimensional polyester porous scaffolds / J Biomed Mater Res 76A:264~271
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
MG-63 cells proliferation following various types of mechanical stimulation on cells by auxetic hybrid scaffolds
생체재료학회지
2016 .12
-
Scaffolds for Tissue Engineering
대한치과재료학회 학술대회
2019 .04
-
A novel gelatin/chitooligosaccharide/demineralized bone matrix composite scaffold and periosteum-derived mesenchymal stem cells for bone tissue engineering
생체재료학회지
2021 .09
-
Mineral deposition and vascular invasion of hydroxyapatite reinforced collagen scaffolds seeded with human adipose-derived stem cells
생체재료학회지
2019 .01
-
Tissue engineering a tendon-bone junction with biodegradable braided scaffolds
생체재료학회지
2019 .01
-
Comparative studies on thin polycaprolactone-tricalcium phosphate composite scaffolds and its interaction with mesenchymal stem cells
생체재료학회지
2019 .01
-
Meniscal Transplants and Scaffolds: A Systematic Review of the Literature
Knee Surgery and Related Research
2017 .01
-
Bioceramic hydroxyapatite-based scaffold with a porous structure using honeycomb as a natural polymeric Porogen for bone tissue engineering
생체재료학회지
2021 .01
-
Micro-CT ? a digital 3D microstructural voyage into scaffolds: a systematic review of the reported methods and results
생체재료학회지
2018 .12
-
3D printed mesh reinforcements enhance the mechanical properties of electrospun scaffolds
생체재료학회지
2019 .01
-
Research and development of dermal scaffolds
대한외과학회 학술대회 초록집
2015 .11
-
Biocompatibility of two experimental scaffolds for regenerative endodontics
Restorative Dentistry and Endodontics
2016 .01
-
Role of offset and gradient architectures of 3-D melt electrowritten scaffold on differentiation and mineralization of osteoblasts
생체재료학회지
2020 .01
-
Study of myoblast differentiation using multi-dimensional scaffolds consisting of nano and micropatterns
생체재료학회지
2017 .03
-
In vivo bone regeneration assessment of offset and gradient melt electrowritten (MEW) PCL scaffolds
생체재료학회지
2020 .01
-
Regeneration of rabbit calvarial defects using cells-implanted nano-hydroxyapatite coated silk scaffolds
생체재료학회지
2015 .06
-
Effect of serum-derived albumin scaffold and canine adipose tissue-derived mesenchymal stem cells on osteogenesis in canine segmental bone defect model
Journal of Veterinary Science
2015 .12
-
Production of Porous Calcium Phosphate (CaP) Ceramics with Aligned Pores using Ceramic/Camphene-based Co-extrusion
생체재료학회지
2015 .09
-
Toward angiogenesis of implanted bio-artificial liver using scaffolds with type I collagen and adipose tissue-derived stem cells
Annals of Hepato-Biliary-Pancreatic Surgery
2015 .05
-
Electrical stimulation as a novel tool for regulating cell behavior in tissue engineering
생체재료학회지
2019 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0