지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.9
- 수록면
- 127 - 133 (7page)
- DOI
- 10.1186/s40824-015-0037-z
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초록· 키워드
오류제보하기
Background: Calcium phosphate (CaP) ceramics are one of the most valuable biomaterials for uses as the bone scaffold owing to their outstanding biocompatability, bioactivity, and biodegradation nature. In particular, these materials with an open porous structure can stimulate bone ingrowth into their 3-dimensionally interconnected pores. However, the creation of pores in bulk materials would inevitably cause a severe reduction in mechanical properties. Thus, it is a challenge to explore new ways of improving the mechanical properties of porous CaP scaffolds without scarifying their high porosity. Results: Porous CaP ceramic scaffolds with aligned pores were successfully produced using ceramic/camphene-based co-extrusion. This aligned porous structure allowed for the achievement of high compressive strength when tested parallel to the direction of aligned pores. In addition, the overall porosity and mechanical properties of the aligned porous CaP ceramic scaffolds could be tailored simply by adjusting the initial CaP content in the CaP/camphene slurry. The porous CaP scaffolds showed excellent in vitro biocompatibility, suggesting their potential as the bone scaffold. Conclusions: Aligned porous CaP ceramic scaffolds with considerably enhanced mechanical properties and tailorable porosity would find very useful applications as the bone scaffold.
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등록된 정보가 없습니다.
참고문헌 (36)
참고문헌 신청
Jones JR. / 2003 / Regeneration of trabecular bone using porous ceramics / Curr Opin Solid St M 7:301~307
Hing KA. / 2005 / Bioceramic bone graft substitutes : influence of porosity and chemistry / Int J Appl Ceram Tech 2:184~199
Dorozhkin SV. / 2010 / Calcium orthophosphates as bioceramics : state of the art / J Funct Biomater 1:22~107
Dorozhkin SV. / 2010 / Bioceramics of calcium orthophosphates / Biomaterials 31:1465~1485
Dorozhkin SV. / 2012 / Biphasic, triphasic and multiphasic calcium orthophosphates / Acta Biomater 8:963~977
Hing KA. / 2005 / Bioceramic bone graft substitutes : influence of porosity and chemistry / Int J Appl Ceram Tech 2:184~199
Dorozhkin SV. / 2010 / Calcium orthophosphates as bioceramics : state of the art / J Funct Biomater 1:22~107
Dorozhkin SV. / 2010 / Bioceramics of calcium orthophosphates / Biomaterials 31:1465~1485
Dorozhkin SV. / 2012 / Biphasic, triphasic and multiphasic calcium orthophosphates / Acta Biomater 8:963~977
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