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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국식품영양과학회 한국식품영양과학회지 한국영양식량학회지 제23권 제5호
발행연도
1994.10
수록면
867 - 878 (12page)

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A general overview of the lipid peroxidation and its nutritional significance are presented, with emphasis on the reaction mechanisms, peroxidized products, further interaction and nutritional / biological deterioration in a series of oxidative processes. Overall mechanism with various factors and elements for initiation, propagation and termination of free radical reaction is reviewed and the primary / secondary products of peroxidized lipids are defined. Since these products are potentially reactive substances that can cause deterioration of proteins /amino acids and vitamins (carotene, tocopherols and ascorbic acid etc), mechanisms and actual damages of their deteriorations in some foods and biological models are outlined. Especially, chemical changes caused by interaction of peroxidized products (related hydroperoxides, radicals and malonaldehyde etc) and protein are emphasized here. And also, the detailed mechanisms on radical scavenging of these vitamins which are the most prominent natural antioxidants are presented. Additionally, the possible roles of peroxidized lipids and their secondary products in the processes of aging and carcinogenesis are briefly discussed. However, it is important to note that more detailed and integrated studies on the reaction kinetics, energetics of peroxidation, their decomposed products, biochemical interaction, potential damaging / aging / carcinogenic effects, protection from their oxidative spoilage and novel antioxidants in food and heterogeneous biological systems will be essential in order to assessing the implication of lipid peroxidation to human nutrition and health.

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Abstract

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과산화반응 메카니즘

과산화반응 생성물들과 단백질 및 아미노산과의 반응

과산화생성물에 의한 노화(老化), 발암(發癌) 기타 질병 유발

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UCI(KEPA) : I410-ECN-0101-2009-511-018073539