지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.6
- 수록면
- 127 - 133 (7page)
이용수
초록· 키워드
오류제보하기
Heterotrimeric GTP binding proteins (G proteins) mediate signal generated by neurotransmitter and hormones. Among all G proteins, Go is the most abundant in brain but its role in brain is not clearly understood. To determine the function of the alpha subunit of Go (Goα), we search for the interacting partner of Goα in brain using yeast two-hybrid system. A resistant to inhibitor of cholinesterase (Ric-8B) was identified as a Goα interacting protein. We confirmed interaction between Goα and Ric-8b employing in vitro affinity binding assay and showed that the Ric-8b increased the function of Goα. Our findings indicate that Ric-8b is possible guanine nucleotide exchange factor for Goα.
목차
서론
재료 및 방법
결과
고찰
감사의 글
REFERENCES
참고문헌 (38)
참고문헌 신청
1. [학술지(정기간행물)] - Ache, BW / 2005 / Olfaction: diverse species, conserved principles / Neuron 48 : 417 ~ 430
2. [학술지(정기간행물)] - Bornancin, F / 1989 / The transitory complex between photoexcited rhodopsin and transducin. Reciprocal interaction between the retinal site in rhodopsin and the nucleotide site in transducin / Eur J Biochem. 184 : 687 ~ 698
3. [학술지(정기간행물)] - Boy-Marcotte, E / 1996 / SDC25, a dispensable Ras guanine nucleotide exchange factor of Saccharomyces cerevisiae differs from CDC25 by its regulation / Mol Biol Cell 7 : 529 ~ 539
4. [학술지(정기간행물)] - Buck, L / 1991 / A novel multigene family may encode odorant receptors: a molecular basis for odor recognition / Cell 65 : 175 ~ 187
5. [학술지(정기간행물)] - Coleman, DE / 1994 / Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis / Science 265 : 1405 ~ 1412
2. [학술지(정기간행물)] - Bornancin, F / 1989 / The transitory complex between photoexcited rhodopsin and transducin. Reciprocal interaction between the retinal site in rhodopsin and the nucleotide site in transducin / Eur J Biochem. 184 : 687 ~ 698
3. [학술지(정기간행물)] - Boy-Marcotte, E / 1996 / SDC25, a dispensable Ras guanine nucleotide exchange factor of Saccharomyces cerevisiae differs from CDC25 by its regulation / Mol Biol Cell 7 : 529 ~ 539
4. [학술지(정기간행물)] - Buck, L / 1991 / A novel multigene family may encode odorant receptors: a molecular basis for odor recognition / Cell 65 : 175 ~ 187
5. [학술지(정기간행물)] - Coleman, DE / 1994 / Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis / Science 265 : 1405 ~ 1412
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UCI(KEPA) : I410-ECN-0101-2009-510-016734723