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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 169 - 171 (3page)
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초록· 키워드
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Chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell disorder characterized by a reciprocal translocation between the long arms of chromosomes 9 and 22, resulting in the formation of a Philadelphia (Ph) chromosome. Most chimeric BCR-ABL1 fusion transcripts are e13a2(b2a2) or e14a2(b3a2), encoding a 210-kDa protein, p210, but some are a e1a2 transcript or e19a2 transcript encoding a 190-kDa protein or a 230-kDa protein, respectively [1]
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참고문헌 (10)
참고문헌 신청
Jain P / 2016 / Impact of BCR-ABL transcript type on outcome in patients with chronic-phase CML treated with tyrosine kinase inhibitors / Blood 127:1269~1275
Demehri S / 2005 / e8a2 BCR-ABL: more frequent than other atypical BCR-ABL variants? / Leukemia 19:681~684
Tchirkov A / 2006 / Major molecular response to imatinib in a patient with chronic myeloid leukemia expressing a novel form of e8a2 BCR-ABL transcript / Leukemia 20:167~168
Riva E / 2015 / A novel e8a2 BCR-ABL1 fusion with insertion of MAST2 exon 2 in a four-way translocation t (1;17;9;22) (p35;q24;q44;q11) in a patient with chronic myeloid leukemia / Leuk Lymphoma 57:203~205
Reid AG / 2004 / A potential role for PRDM12 in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion / Leukemia 18:178~180
Demehri S / 2005 / e8a2 BCR-ABL: more frequent than other atypical BCR-ABL variants? / Leukemia 19:681~684
Tchirkov A / 2006 / Major molecular response to imatinib in a patient with chronic myeloid leukemia expressing a novel form of e8a2 BCR-ABL transcript / Leukemia 20:167~168
Riva E / 2015 / A novel e8a2 BCR-ABL1 fusion with insertion of MAST2 exon 2 in a four-way translocation t (1;17;9;22) (p35;q24;q44;q11) in a patient with chronic myeloid leukemia / Leuk Lymphoma 57:203~205
Reid AG / 2004 / A potential role for PRDM12 in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion / Leukemia 18:178~180
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