지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.4
- 수록면
- 275 - 282 (8page)
이용수
초록· 키워드
오류제보하기
STAR of STAR (SS 01-04) is a series of drinks that consist of various extracts obtained from Coriolus versicolor, Artemisia capillaris Thunb., Hovenia dulcis, Acanthopanax sessiliflorus, Lycium chinense, Citrus reticulata, Saururus chinensis, Pueraria lobata, Pyrus pyrifolia, and Oenanthe javanica. A purpose of this study was to investigate the hepatoprotective effect of SS 01-04. Antioxidant activity of the drinks was evaluated by conducting a hydroxyl radical-scavenging assay. Cytotoxicity and hepatoprotective potential were determined using HepG2 cells in vitro, while protective effects against acute hepatotoxicity was evaluated in vivo. The antioxidant activity of the SS 01-04 at concentration of 100 and 250 mg/mL was similar to that of 50 μM vitamin C. tert-Butyl hydroperoxide (tBHP)-induced production of reactive oxygen species (ROS) was blocked by SS 01, 03 and 04 in a dose-dependent manner. Treatment with SS 04 significantly lowered the serum levels of alanine aminotransferase and aspartate aminotransferase in an animal model of carbon tetrachloride (CCl<sub>4</sub>)-induced hepatotoxicity (p<0.05). In addition, SS04 increased glutathione level while decreased malondialdehyde level in the liver considerably (p<0.05). It also inhibited the CCl<sub>4</sub>-induced increase in the levels of triglyceride and cholesterol in serum and the liver. These findings indicated that SS 01-04 possessed antioxidant activity and protect against ROS. In particular, SS 04 is potentially highly beneficial in treating liver damage as it scavenges reactive free radicals and boosts the endogenous antioxidant system.
목차
등록된 정보가 없습니다.
참고문헌 (35)
참고문헌 신청
[학술지(정기간행물)] - 연성호 / 2013 / tert-Butyl Hydroperoxide로 산화 스트레스가 유도된 HepG2 세포에서 말채나무 열수추출물의 항산화 활성 / 한국식품영양과학회지 42 (10) : 1525 ~ 1532
[학술지(정기간행물)] - Hazem K. Ghneim / 2016 / Biochemical Markers of Oxidative Stress in Saudi Women with Recurrent Miscarriage / Journal of Korean Medical Science 31 (1) : 98 ~ 105
[학술지(정기간행물)] - Mourao Mde M / 2009 / Role of the endogenous antioxidant system in the protection of Schistosoma mansoni primary sporocysts against exogenous oxidative stress / PLoS Negl Trop Dis 17 : 550 ~ 562
[학술지(정기간행물)] - Jin X / 2015 / The protective effects of Masson pine pollen aqueous extract on CCl4-induced oxidative damage of human hepatic cells / Int J Clin Exp Med 8 : 17773 ~ 17780
[학술지(정기간행물)] - de Andrade KQ / 2015 / Oxidative stress and inflammation in hepatic diseases: therapeutic possibilities of N-Acetylcysteine / Int J Mol Sci 37 : 30269 ~ 30308
[학술지(정기간행물)] - Hazem K. Ghneim / 2016 / Biochemical Markers of Oxidative Stress in Saudi Women with Recurrent Miscarriage / Journal of Korean Medical Science 31 (1) : 98 ~ 105
[학술지(정기간행물)] - Mourao Mde M / 2009 / Role of the endogenous antioxidant system in the protection of Schistosoma mansoni primary sporocysts against exogenous oxidative stress / PLoS Negl Trop Dis 17 : 550 ~ 562
[학술지(정기간행물)] - Jin X / 2015 / The protective effects of Masson pine pollen aqueous extract on CCl4-induced oxidative damage of human hepatic cells / Int J Clin Exp Med 8 : 17773 ~ 17780
[학술지(정기간행물)] - de Andrade KQ / 2015 / Oxidative stress and inflammation in hepatic diseases: therapeutic possibilities of N-Acetylcysteine / Int J Mol Sci 37 : 30269 ~ 30308
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Hepatoprotection of chitosan-caffeic acid conjugate against oxidative stress through up-regulation of ERK and Nrf2-mediated phase II detoxifying/antioxidant enzymes
한국식품영양과학회 학술대회발표집
2016 .10
-
LPS-induced Macrophages Require Reactive Oxygen and Nitrogen Species for Survival in Early Infection
한국식품영양과학회 학술대회발표집
2015 .08
-
학생 말하기 교육에 K-Star+ 교수법 적용 및 효과성 연구
수산해양교육연구
2023 .10
-
적미 미강 추출 분획물의 항산화 활성
한국식품영양과학회지
2019 .01
-
Protective Role of P-Coumaric Acid on Acetaminophen-Induced Hepatotoxicity
한국식품영양과학회 학술대회발표집
2017 .10
-
Antioxidative Effects and Hepatoprotection in Cell based Assay of Raphanus sativus L. var niger Extracts
한국식품영양과학회 학술대회발표집
2016 .10
-
밝은 적색 조경용 소형철쭉 ‘스몰스타(Small Star)’ 육성
한국원예학회 학술발표요지
2020 .11
-
Growth Characteristics of Doritaenopsis ‘Super Star’ as Affected by CO₂
한국원예학회 학술발표요지
2015 .05
-
Effects of S-adenosylmethionine and its combinations with taurine and/or betaine on glutathione homeostasis in ethanol-induced acute hepatotoxicity
한국식품영양과학회 학술대회발표집
2016 .10
-
Different shapes of Al<sub>2</sub>O<sub>3</sub> particles induce differential cytotoxicity via a mechanism involving lysosomal destabilization and reactive oxygen species generation
Applied Biological Chemistry
2015 .01
-
Protective effect screening of vitamins against PFOA-induced hepatotoxicity in HepG2 cells
한국식품영양과학회 학술대회발표집
2023 .10
-
허브간장의 항산화성 및 품질 특성에 미치는 영향
한국식품영양학회지
2020 .01
-
Protective Effect of Dendropanax morbifera Leaf Extracts on Ethanol Induced Hepatotoxicity in Mice
한국식품영양과학회 학술대회발표집
2017 .10
-
Effect of sea mustard fractions on production of reactive oxygen species and cellular DNA oxidation
한국식품영양과학회 학술대회발표집
2024 .10
-
Tuberatolide B Inhibits Tumor Progression by Inducing Reactive Oxygen Species-mediated Suppression of STAT3 Activation
한국식품영양과학회 학술대회발표집
2019 .10
-
Inhibitory Effects of Caffeic Acid Phenethyl Ester on Adipocyte Differentiation through Regulation of Reactive Oxygen Species in 3T3-L1 Cell Model
한국식품영양과학회 학술대회발표집
2016 .10
-
Protective effects of S-adenosylmethionine and its combinations with taurine and/or betaine against lipopolysaccharide or polyinosinic-polycytidylic acid-induced acute hepatotoxicity
한국식품영양과학회 학술대회발표집
2016 .10
-
약선죽(藥膳粥)에 대한 인지도 및 메뉴 개발 방향 - 대전지역 성인 여성을 중심으로 -
대한영양사협회 학술지
2017 .01
-
Effects of Ligularia stenocephala Extracts on Antioxidation, Cytotoxicity, Hepatoprotection, Alcohol Detoxication, and Memory Improvement in vitro or in vivo
한국식품영양과학회 학술대회발표집
2015 .08
-
Effect of rudder fish extracts on production of glutathione (GSH) and reactive oxygen species (ROS)
한국식품영양과학회 학술대회발표집
2024 .10
이 논문의 저자 정보
이 논문과 함께 이용한 논문
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2018-059-003060651