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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.2 No.2
- 발행연도
- 1997.6
- 수록면
- 138 - 143 (6page)
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Crude catechin extracts were prepared using ethyl acetate from Korean Puerariae Radix(PR) and their biological effects on the alcoholic liver damage were investigated in male Sprague-Dawley rats(6 weeks old). Ethanol(5g ethanol/㎏ body weight/day) administration was performed for 8 weeks and after ethanol consuming rats were treated with one or two% catechin extracts of diet for 8 weeks. At the end of experimental period, lipid hydroperoxides in liver were analyzed using a chemiluminescence-high performance liquid chromatography(CL-HPLC) method. Compared with control animals, ethanol consumed rats showed lighter body weights, lower ratios of liver/body weight, higher activities of GOT and GPT, and increased lipid hydroperoxide amount in liver. With one or two% catechin extracts treatment, GOT and GPT activites returned to normal ranges. Lipid hydroperoxide contents in liver of one or two% PR treated rats lowered to 20% or 25% respectively, compared with the levels of those ethanol consumed animals without catechin extracts treatment. Therefore, we concluded that one or two% PR crude catechins treatment could be effective for alcoholic liver damage caused by lipid peroxidation.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
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