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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
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- 학술저널
- 저자정보
- 발행연도
- 2003.3
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- 1 - 6 (6page)
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Catechins exhibit a hypocholesterolemic effect in cholesterol-fed animals. The present study was conducted to examine whether (+)-catechin influences the absorption of cholesterol in rats. Male Sprague-Dawley rats were fed ad libitum an AIN-93G diet containing soybean oil for 5 wk. Rats with lymph cannulae were infused at 3.0 mL/h for 8 h via a duodenal catheter with a lipid emulsion containing radiolabeled cholesterol with or without (+)-catechin. Lymph was collected hourly for 8 h. The enteral infusion of (+)-catechin significantly lowered the lymphatic absorption of (14)^C-cholesterol (21.1±3.6% dose/8 h) compared with controls infused with the lipid emulsion devoid of (+)-catechin (38.2±1.2% dose/8 h). The intestinal absorption of α-tocopherol (24.2±3.0% dose/8 h) also was significantly decreased by (+)-catechin infusion, relative to controls (32.2±2.2% dose/8 h). However, the lymphatic outputs of oleic acid, phospholipid were not affected by enteral (+)-catechin infusion. The results indicate that (+)-catechin has a profound inhibitory effect on the intestinal absorption of cholesterol, α-tocopherol without affecting the absorption of fat.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
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UCI(KEPA) : I410-ECN-0101-2009-511-018078903