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Antioxidant and Whitening Effects of Lotus (Nelumbo nucifera) Seeds Extract through Tyrosinase Inhibition
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연자육 추출물의 항산화 및 미백 활성 평가

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Type
Academic journal
Author
Su-Hyeun Hwang (경남대학교) Gyo-Nam Kim (경남대학교)
Journal
The East Asian Society Of Dietary Life Journal of the East Asian Society of Dietary Life Vol.33 No.3 KCI Accredited Journals
Published
2023.6
Pages
233 - 240 (8page)
DOI
10.17495/easdl.2023.6.33.3.233

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Antioxidant and Whitening Effects of Lotus (Nelumbo nucifera) Seeds Extract through Tyrosinase Inhibition
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This study examined whether the ethanol extract of lotus (Nelumbo nucifera) seeds (EL) has potential use functional food materials. Its antioxidant effect was evaluated by measuring its DPPH radical scavenging activity and reduction potential. In addition, its whitening activity was evaluated through its ability to inhibit tyrosinase, which binds to L-DOPA and contributes to melanin formation in the initial stage of melanogenesis. The EL treatment exhibited a dose-dependent increase in the total phenolic assay, DPPH radical scavenging, and reduction potential. The total phenolic content of EL at concentrations of 100, 250, 500, 750, and 1,000 μg/mL was measured as 4.32, 9.92, 18.42, 25.02, and 29.67 GAE μg/mL, respectively. The DPPH radical scavenging assay indicated inhibition of 4.28%, 9.56%, 11.02%, 24.77%, and 37.28% for the EL treatment at concentrations of 1, 5, 10, 25, and 50 μg/mL, respectively, compared to the control (no treatment). Furthermore, the reduction potential of EL was 0.79, 3.92, 8.11, 20.88, and 33.48 μM at concentrations of 1, 5, 10, 25, and 50 μg/mL, respectively. The whitening effect of the EL treatment showed inhibitory activities of 18.88%, 25.48%, 41.21%, 69.87%, and 89.65%. These results suggest EL could be used as a functional food material because of its antioxidant activity.
#lotus (Nelumbo nucifera) seeds #antioxidant #whitening activity #natural product #functional foods

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